Article
How I treat Philadelphia chromosome-positive acute lymphoblastic leukemia.
Blood - 4 Nov 2010
Fielding Adele K
Abstract excerpt
The Philadelphia chromosome is present in approximately 20% to 30% of adults with acute lymphoblastic leukemia (ALL). The poor prognosis of this relatively uncommon acute leukemia has led to the rapid adoption of treatment strategies such as unrelated donor hematopoietic stem cell transplant and tyrosine kinase inhibitors into clinical practice, despite a relative paucity of randomized clinical trials. Recently,...
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