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Article

Genotype-Associated Differential NKG2D Expression on CD56+CD3+ Lymphocytes Predicts Response to Pegylated-Interferon/Ribavirin Therapy in Chronic Hepatitis C.

PloS one - 1 Jan 2015

Chu Po-sung, Ebinuma Hirotoshi, Nakamoto Nobuhiro, Sugiyama Kazuo, Usui Shingo, Wakayama Yuko, Taniki Nobuhito, Yamaguchi Akihiro, Shiba Shunsuke, Yamagishi Yoshiyuki, Wakita Takaji, Hibi Toshifumi, Saito Hidetsugu, Kanai Takanori

Abstract excerpt

Hepatitis C virus (HCV) genotype 1 infections are significantly more difficult to eradicate with PEG-IFN/ribavirin therapy, compared to HCV genotype 2. The aim of this work is to investigate the difference of immunological impairments underlying this phenomenon. Pre-treatment NKG2D expression on...

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Identifiers

PMID: 25965701
DOI: 10.1371/journal.pone.0125664
PMCID: PMC4428701

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25965701-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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