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Article

Cutting edge: Bcl6-interacting corepressor contributes to germinal center T follicular helper cell formation and B cell helper function.

Journal of immunology (Baltimore, Md. : 1950) - 15 Jun 2015

Yang Jessica A, Tubo Noah J, Gearhart Micah D, Bardwell Vivian J, Jenkins Marc K

Abstract excerpt

CD4(+) germinal center (GC)-T follicular helper (Tfh) cells help B cells become long-lived plasma cells and memory cells. The transcriptional repressor Bcl6 plays a key role in GC-Tfh formation by inhibiting the expression of genes that promote differentiation into other lineages. We determined whether BCOR, a component of a Polycomb repressive complex that interacts with the Bcl6 BTB domain, influences GC-Tfh...

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Source

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Identifiers

PMID: 25964495
DOI: 10.4049/jimmunol.1500201
PMCID: PMC4458443

Genes

BCOR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

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