Article
Adaptive evolution of Hoxc13 genes in the origin and diversification of the vertebrate integument.
Journal of experimental zoology. Part B, Molecular and developmental evolution - 1 Nov 2013
Wu Jianghong, Husile, Sun Hailian, Wang Feng, Li Yurong, Zhao Cunfa, Zhang Wenguang
Abstract excerpt
The problem of origination and diversification of integument derivatives in vertebrates is still a challenge. The homeobox (Hox) genes Hoxc13 control integument formation in vertebrate. Hoxc13 show strong expression in the integument development, are highly conserved across vertebrates, and show mutations that are associated with skin and appendages. To test whether the evolution of the integument is associated...
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