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Article

Control of colinearity in AbdB genes of the mouse HoxD complex.

Molecular cell - 1 Jan 1998

Kondo T, Zákány J, Duboule D

Abstract excerpt

During development, vertebrate Hox genes are activated in a temporal and spatial sequence colinear with the position of the genes within their clusters. To investigate the mechanistic basis of this phenomenon, we used the ES cell technology and the loxP/Cre system to engineer a conditional fusion of the 5' exon of Hoxd-13 with the 3' exon of Hoxd-12. This hybrid transcription unit was regulated like Hoxd-11, with...

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PMID: 9659925
DOI: 10.1016/s1097-2765(00)80029-5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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