Article
Control of colinearity in AbdB genes of the mouse HoxD complex.
Molecular cell - 1 Jan 1998
Kondo T, Zákány J, Duboule D
Abstract excerpt
During development, vertebrate Hox genes are activated in a temporal and spatial sequence colinear with the position of the genes within their clusters. To investigate the mechanistic basis of this phenomenon, we used the ES cell technology and the loxP/Cre system to engineer a conditional fusion...
Topics
- Alleles
- Animals
- Drosophila Proteins
- Female
- Gene Deletion
- Gene Expression Regulation, Developmental
- Genes, Homeobox
- Homeodomain Proteins
- Mice
- Mice, Inbred C57BL
- Mice, Transgenic
- Mutagenesis
- Phenotype
- Promoter Regions, Genetic
- Recombinant Proteins
- Transcription Factors
- Transgenes
- Zebrafish