Article
DNA repair genes XRCC1 and ERCC1 polymorphisms and the risk of sporadic breast cancer in Han women in the Gansu Province of China.
Genetic testing and molecular biomarkers - 1 Jul 2015
Zhu Gongjian, Wang Lan, Guo Hongyun, Lu Lingeng, Yang Suisheng, Wang Tao, Guo Huan, Wang Haitao, Min Jianping, Yang Kai, Chen Xuezhong, Liu Yuanqiang, Wang Zhiping, Su Haixiang
Abstract excerpt
AIMS: Polymorphisms in DNA damage repair genes may affect DNA repair capacity and modulate breast cancer susceptibility. In this study, we aimed to analyze two polymorphisms for each of the DNA repair genes X-ray repair cross-complementing group 1 (XRCC1) rs25487 and rs1799782 and excision repair cross-complementing group 1 (ERCC1) rs3212964 and rs11615, to evaluate their associations with the risk of sporadic...
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