Article
The relationship between five non-synonymous polymorphisms within three XRCC genes and gastric cancer risk in a Han Chinese population.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 May 2016
Gong Huansong, Li He, Zou Jing, Mi Jia, Liu Fang, Wang Dan, Yan Dong, Wang Bin, Zhang Shuping, Tian Geng
Abstract excerpt
We aimed to assess the association of five non-synonymous polymorphisms within three X-ray repair cross-complementing group (XRCC) genes with gastric cancer risk in Han Chinese. Genotyping was determined in 693 gastric cancer patients and 681 healthy controls. Statistical analyses were completed with SPSS (version 20.0) and Haplo.stats (version 1.6.11). The genotypes of XRCC1 gene rs25487 polymorphism (P = 0.003)...
Topics
- Aged
- Alleles
- Asian People
- Case-Control Studies
- China
- DNA-Binding Proteins
- Female
- Gene Frequency
- Genetic Predisposition to Disease
- Genotype