Article
Coexpression Pattern Analysis of NPM1-Associated Genes in Chronic Myelogenous Leukemia.
BioMed research international - 1 Jan 2015
Wang Fengfeng, Chan Lawrence W C, Tsui Nancy B Y, Wong S C Cesar, Siu Parco M, Yip S P, Yung Benjamin Y M
Abstract excerpt
BACKGROUND: Nucleophosmin 1 (NPM1) plays an important role in ribosomal synthesis and malignancies, but NPM1 mutations occur rarely in the blast-crisis and chronic-phase chronic myelogenous leukemia (CML) patients. The NPM1-associated gene set (GCM_NPM1), in total 116 genes including NPM1, was chosen as the candidate gene set for the coexpression analysis. We wonder if NPM1-associated genes can affect the...
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