Article
Identification of Common Genes and Pathways Underlying Imatinib and Nilotinib Treatment in CML: a Bioinformatics Study
2023-08-31
Abstract excerpt
<title>Abstract</title> <p>Imatinib (IMA) and nilotinib are the first and second generations of BCR-ABL tyrosine kinase inhibitors which widely applied in chronic myeloid leukemia (CML) treatment. Here we aimed to provide new targets for CML treatment by transcriptome analysis. Microarray data GSE19567 was downloaded and analyzed from Gene Expression Omnibus (GEO) to identify common genes which are downregulated...
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Identifiers and source
- Literature Corpus work
- 9d6af804-dfbc-5a7d-8975-05ef29e9c9a8
- DOI
- 10.21203/rs.3.rs-3291987/v1
