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Article

ProtPhylo: identification of protein-phenotype and protein-protein functional associations via phylogenetic profiling.

Nucleic acids research - 1 Jul 2015

Cheng Yiming, Perocchi Fabiana

Abstract excerpt

ProtPhylo is a web-based tool to identify proteins that are functionally linked to either a phenotype or a protein of interest based on co-evolution. ProtPhylo infers functional associations by comparing protein phylogenetic profiles (co-occurrence patterns of orthology relationships) for more than 9.7 million non-redundant protein sequences from all three domains of life. Users can query any of 2048 fully...

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Identifiers

PMID: 25956654
DOI: 10.1093/nar/gkv455
PMCID: PMC4489284

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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