Article

FASSO: An AlphaFold based method to assign functional annotations by combining sequence and structure orthology

2022-11-15

Abstract excerpt

<h4>Methods: </h4> to predict orthology play an important role in bioinformatics for phylogenetic analysis by identifying orthologs within or across any level of biological classification. Sequence-based reciprocal best hit approaches are commonly used in functional annotation since orthologous genes are expected to share functions. The process is limited as it relies solely on sequence data and does not consider...

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Literature Corpus work: c4e65b24-72e4-50b6-b6b3-9b1b8dd57fd7
DOI: 10.1101/2022.11.10.516002

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