Article
Comparative analysis of type 2 diabetes-associated SNP alleles identifies allele-specific DNA-binding proteins for the KCNQ1 locus.
International journal of molecular medicine - 1 Jul 2015
Hiramoto Masaki, Udagawa Haruhide, Watanabe Atsushi, Miyazawa Keisuke, Ishibashi Naoko, Kawaguchi Miho, Uebanso Takashi, Nishimura Wataru, Nammo Takao, Yasuda Kazuki
Abstract excerpt
Although recent genome-wide association studies (GWAS) have been extremely successful, it remains a big challenge to functionally annotate disease‑associated single nucleotide polymorphisms (SNPs), as the majority of these SNPs are located in non‑coding regions of the genome. In this study, we de...
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