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Article

The p38α mitogen-activated protein kinase is a key regulator of myelination and remyelination in the CNS.

Cell death & disease - 7 May 2015

Chung S-H, Biswas S, Selvaraj V, Liu X-B, Sohn J, Jiang P, Chen C, Chmilewsky F, Marzban H, Horiuchi M, Pleasure D E, Deng W

Abstract excerpt

The p38α mitogen-activated protein kinase (MAPK) is one of the serine/threonine kinases regulating a variety of biological processes, including cell-type specification, differentiation and migration. Previous in vitro studies using pharmacological inhibitors suggested that p38 MAPK is essential for oligodendrocyte (OL) differentiation and myelination. To investigate the specific roles of p38α MAPK in OL...

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Identifiers

PMID: 25950478
DOI: 10.1038/cddis.2015.119
PMCID: PMC4669698

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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