Article
Deletion of Jun proteins in adult oligodendrocytes does not perturb cell survival, or myelin maintenance in vivo.
PloS one - 1 Jan 2015
Schreiner Bettina, Ingold-Heppner Barbara, Pehl Debora, Locatelli Giuseppe, Berrit-Schönthaler Helia, Becher Burkhard
Abstract excerpt
Oligodendrocytes, the myelin-forming glial cells of the central nervous system (CNS), are fundamental players in rapid impulse conduction and normal axonal functions. JunB and c-Jun are DNA-binding components of the AP-1 transcription factor, which is known to regulate different processes such as proliferation, differentiation, stress responses and death in several cell types, including cultured...
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