Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Role of Mitochondrial DNA Damage in ROS-Mediated Pathogenesis of Age-Related Macular Degeneration (AMD)

14 May 2019

Abstract excerpt

Age-related macular degeneration (AMD) is a complex eye disease that affects millions of people worldwide and is the main reason for legal blindness and vision loss in the elderly in developed countries. Although the cause of AMD pathogenesis is not known, oxidative stress-related damage to retinal pigment epithelium (RPE) is considered an early event in AMD induction. However, the precise cause of such damage...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Ocular Diseases and Behçet’s Syndrome
Share to Retinal Development and Disorders
Share to Retinal Diseases and Treatments

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 31091656
DOI: 10.3390/ijms20102374

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Role of Mitochondrial DNA Damage in ROS-Mediated Pathogenesis of Age-Related Macular Degeneration (AMD)PMID 31091656Read ↗

Mitochondrial and Nuclear DNA Damage and Repair in Age-Related Macular DegenerationSemantic proximity Read ↗

Mitochondrial Dysfunction in Retinal DiseasesSemantic proximity Read ↗

Mitochondrial dysfunction in age-related macular degeneration: melatonin as a potential treatmentSemantic proximity Read ↗

Oxidative stress-induced mitochondrial DNA damage in human retinal pigment epithelial cells: a possible mechanism for RPE aging and age-related macular degenerationSemantic proximity Read ↗

Mitochondrial DNA Damage as a Potential Mechanism for Age-Related Macular DegenerationSemantic proximity Read ↗

Investigating Mitochondria as a Target for Treating Age-Related Macular DegenerationSemantic proximity Read ↗

Oxidation and age-related macular degeneration: insights from molecular biologySemantic proximity Read ↗

Mitochondrial DNA damage and repair in RPE associated with aging and age-related macular degeneration.Semantic proximity Read ↗

Age-Related Macular Degeneration and Mitochondria-Associated Autoantibodies: A Review of the Specific Pathogenesis and Therapeutic StrategiesSemantic proximity Read ↗

Central Role of Oxidative Stress in Age-Related Macular Degeneration: Evidence from a Review of the Molecular Mechanisms and Animal ModelsSemantic proximity Read ↗

Molecular mechanisms of retinal pigment epithelium damage and development of age-related macular degeneration.Semantic proximity Read ↗

Mitochondrial DNA damage and its potential role in retinal degenerationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.