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Article

Mitochondrial dysfunction in age-related macular degeneration: melatonin as a potential treatment

2 Mar 2020

Abstract excerpt

Introduction: Age-related Macular Degeneration (AMD), a retinal neurodegenerative disease is the most common cause of blindness among the elderly in developed countries. The impairment of mitochondrial biogenesis has been reported in human retinal pigment epithelium (RPE) cells affected by AMD. Oxidative/nitrosative stress plays an important role in AMD development. The mitochondrial respiratory system is...

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Share to Circadian rhythm and melatonin
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PMID: 32116056
DOI: 10.1080/14728222.2020.1737015

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