Article
[BRAF V600E Mutation in Chinese Patients with Langerhans Cell Histiocytosis and Its Clinical Significance].
Zhongguo shi yan xue ye xue za zhi - 1 Apr 2015
Cheng Xiao-Ye, Li Yan, Zhou Jun, Shu Yi-Gang, Li Xiao-Lin, Fu Bin
Abstract excerpt
OBJECTIVE: To investigate the BRAF V600E mutation in Chinese patients with langerhans cell histiocytosis (LCH) and its clinical significance. METHODS: The clinical records of 50 pathology-diagnosed LCH cases were analyzed retrospectively and the Paraffin-embedded tissue blocks were retrieved to test the BRAF V600E mutation by immunohistochemical method with a specific BRAF V600E protein antibody. BRAF V600E...
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