Brain structure-function associations in multi-generational families genetically enriched for bipolar disorder.

doi:10.1093/brain/awv106

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Brain structure-function associations in multi-generational families genetically enriched for bipolar disorder.

Brain : a journal of neurology - 1 Jul 2015

Fears Scott C, Schür Remmelt, Sjouwerman Rachel, Service Susan K, Araya Carmen, Araya Xinia, Bejarano Julio, Knowles Emma, Gomez-Makhinson Juliana, Lopez Maria C, Aldana Ileana, Teshiba Terri M, Abaryan Zvart, Al-Sharif Noor B, Navarro Linda, Tishler Todd A, Altshuler Lori, Bartzokis George, Escobar Javier I, Glahn David C, Thompson Paul M, Lopez-Jaramillo Carlos, Macaya Gabriel, Molina Julio, Reus Victor I, Sabatti Chiara, Cantor Rita M, Freimer Nelson B, Bearden Carrie E

Abstract excerpt

Recent theories regarding the pathophysiology of bipolar disorder suggest contributions of both neurodevelopmental and neurodegenerative processes. While structural neuroimaging studies indicate disease-associated neuroanatomical alterations, the behavioural correlates of these alterations have not been well characterized. Here, we investigated multi-generational families genetically enriched for bipolar disorder...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adolescent

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Aged, 80 and over

Share to Bipolar Disorder

Share to Brain

Share to Image Interpretation, Computer-Assisted

Share to Magnetic Resonance Imaging

Share to Psychiatric Status Rating Scales

Share to Young Adult

Source

Open in PubMed Open full text

Identifiers

PMID: 25943422
DOI: 10.1093/brain/awv106
PMCID: PMC4572484

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Brain structure-function associations in multi-generational families genetically enriched for bipolar disorder.PMID 25943422Read ↗

Genome-wide mapping of brain phenotypes in extended pedigrees with strong genetic loading for bipolar disorder.Semantic proximity Read ↗

Multisystem component phenotypes of bipolar disorder for genetic investigations of extended pedigrees.Semantic proximity Read ↗

Genetic and neuroanatomical correlates of bipolar disorder in high-risk youth.Semantic proximity Read ↗

Intelligence, educational attainment, and brain structure in those at familial high-risk for schizophrenia or bipolar disorder.Semantic proximity Read ↗

Genetic risk for bipolar disorder and schizophrenia predicts structure and function of the ventromedial prefrontal cortex.Semantic proximity Read ↗

Structural neuroimaging phenotypes of a novel multi-gene risk score in youth bipolar disorder.Semantic proximity Read ↗

Heritability of cognitive functions in families with bipolar disorder.Semantic proximity Read ↗

Genetic analysis of activity, brain and behavioral associations in extended families with heavy genetic loading for bipolar disorder.Semantic proximity Read ↗

Brain structural signature of familial predisposition for bipolar disorder: replicable evidence for involvement of the right inferior frontal gyrus.Semantic proximity Read ↗

Using structural MRI to identify individuals at genetic risk for bipolar disorders: a 2-cohort, machine learning study.Semantic proximity Read ↗

Gray matter abnormalities as brain structural vulnerability factors for bipolar disorder: A review of neuroimaging studies of individuals at high genetic risk for bipolar disorder.Semantic proximity Read ↗

Clinical, genetic, and brain imaging predictors of risk for bipolar disorder in high-risk individuals.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.