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Article

Brain structural signature of familial predisposition for bipolar disorder: replicable evidence for involvement of the right inferior frontal gyrus.

Biological psychiatry - 15 Jan 2013

Hajek Tomas, Cullis Jeffrey, Novak Tomas, Kopecek Miloslav, Blagdon Ryan, Propper Lukas, Stopkova Pavla, Duffy Anne, Hoschl Cyril, Uher Rudolf, Paus Tomas, Young L Trevor, Alda Martin

Abstract excerpt

BACKGROUND: To translate our knowledge about neuroanatomy of bipolar disorder (BD) into a diagnostic tool, it is necessary to identify the neural signature of predisposition for BD and separate it from effects of long-standing illness and treatment. Thus, we examined the associations among genetic risk, illness burden, lithium treatment, and brain structure in BD. METHODS: This is a two-center,...

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Identifiers

PMID: 22818781
DOI: 10.1016/j.biopsych.2012.06.015
PMCID: PMC4830692

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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