Genetic analysis of activity, brain and behavioral associations in extended families with heavy genetic loading for bipolar disorder.

doi:10.1017/S0033291719003416

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Article

Genetic analysis of activity, brain and behavioral associations in extended families with heavy genetic loading for bipolar disorder.

Psychological medicine - 1 Feb 2021

Vreeker Annabel, Fears Scott C, Service Susan K, Pagani Lucia, Takahashi Joseph S, Araya Carmen, Araya Xinia, Bejarano Julio, Lopez Maria C, Montoya Gabriel, Montoya Claudia Patricia, Teshiba Terri M, Escobar Javier, Cantor Rita M, López-Jaramillo Carlos, Macaya Gabriel, Molina Julio, Reus Victor I, Sabatti Chiara, Ophoff Roel A, Freimer Nelson B, Bearden Carrie E

Abstract excerpt

BACKGROUND: Disturbed sleep and activity are prominent features of bipolar disorder type I (BP-I). However, the relationship of sleep and activity characteristics to brain structure and behavior in euthymic BP-I patients and their non-BP-I relatives is unknown. Additionally, underlying genetic relationships between these traits have not been investigated. METHODS: Relationships between sleep and activity...

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PMID: 31813409
DOI: 10.1017/S0033291719003416

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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