Multisystem component phenotypes of bipolar disorder for genetic investigations of extended pedigrees.

doi:10.1001/jamapsychiatry.2013.4100

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Multisystem component phenotypes of bipolar disorder for genetic investigations of extended pedigrees.

JAMA psychiatry - 1 Apr 2014

Fears Scott C, Service Susan K, Kremeyer Barbara, Araya Carmen, Araya Xinia, Bejarano Julio, Ramirez Margarita, Castrillón Gabriel, Gomez-Franco Juliana, Lopez Maria C, Montoya Gabriel, Montoya Patricia, Aldana Ileana, Teshiba Terri M, Abaryan Zvart, Al-Sharif Noor B, Ericson Marissa, Jalbrzikowski Maria, Luykx Jurjen J, Navarro Linda, Tishler Todd A, Altshuler Lori, Bartzokis George, Escobar Javier, Glahn David C, Ospina-Duque Jorge, Risch Neil, Ruiz-Linares Andrés, Thompson Paul M, Cantor Rita M, Lopez-Jaramillo Carlos, Macaya Gabriel, Molina Julio, Reus Victor I, Sabatti Chiara, Freimer Nelson B, Bearden Carrie E

Abstract excerpt

IMPORTANCE: Genetic factors contribute to risk for bipolar disorder (BP), but its pathogenesis remains poorly understood. A focus on measuring multisystem quantitative traits that may be components of BP psychopathology may enable genetic dissection of this complex disorder, and investigation of extended pedigrees from genetically isolated populations may facilitate the detection of specific genetic variants that...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bipolar Disorder

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cerebral Cortex

Share to Genetic Linkage

Share to Magnetic Resonance Imaging

Share to Neuropsychological Tests

Share to Organ Size

Share to Statistics as Topic

Share to Temperament

Source

Open in PubMed Open full text

Identifiers

PMID: 24522887
DOI: 10.1001/jamapsychiatry.2013.4100
PMCID: PMC4045237

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Multisystem component phenotypes of bipolar disorder for genetic investigations of extended pedigrees.PMID 24522887Read ↗

Genome-wide mapping of brain phenotypes in extended pedigrees with strong genetic loading for bipolar disorder.Semantic proximity Read ↗

Brain structure-function associations in multi-generational families genetically enriched for bipolar disorder.Semantic proximity Read ↗

Contribution of common and rare variants to bipolar disorder susceptibility in extended pedigrees from population isolates.Semantic proximity Read ↗

Structural neuroimaging phenotypes of a novel multi-gene risk score in youth bipolar disorder.Semantic proximity Read ↗

Neurocognitive endophenotypes for bipolar disorder identified in multiplex multigenerational families.Semantic proximity Read ↗

Assessment of first and second degree relatives of individuals with bipolar disorder shows increased genetic risk scores in both affected relatives and young At-Risk Individuals.Semantic proximity Read ↗

A narrow and highly significant linkage signal for severe bipolar disorder in the chromosome 5q33 region in Latin American pedigrees.Semantic proximity Read ↗

Genetic substrates of bipolar disorder risk in Latino families.Semantic proximity Read ↗

Clinical, genetic, and brain imaging predictors of risk for bipolar disorder in high-risk individuals.Semantic proximity Read ↗

Estimating the Heritability of Structural and Functional Brain Connectivity in Families Affected by Attention-Deficit/Hyperactivity Disorder.Semantic proximity Read ↗

A Multi-Dimensional and Integrative Approach to Examining the High-Risk and Ultra-High-Risk Stages of Bipolar DisorderSemantic proximity Read ↗

Genetic and neuroanatomical correlates of bipolar disorder in high-risk youth.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.