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Interleukin-10-592 Polymorphism: Impact on Relapse and Survival After Allogeneic Hematopoietic Stem Cell Transplantation in Children With Hematological Malignancies

2021-04-21

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<title>Abstract</title> <p><bold>Purpose </bold>Interleukin-10 (IL-10) potentially can promote the development of alloimmunity. The aim of this study was to investigate if the IL-10-592 CC genotype in the donor reduces the risk of relapse after hematopoietic stem cell transplantation (HSCT) and if that has an impact on event-free survival (EFS) and overall survival (OS).<bold>Methods</bold> A cohort of 211 childr...

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Literature Corpus work
22929dce-1524-5de4-8a08-00f1153595c8
DOI
10.21203/rs.3.rs-440571/v1
Open publication

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Interleukin-10-592 Polymorphism: Impact on Relapse and Survival After Allogeneic Hematopoietic Stem Cell Transplantation in Children With Hematological MalignanciesDOI 10.21203/rs.3.rs-440571/v1
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