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Article

IL-10 promoter polymorphisms affect IL-10 production and associate with susceptibility to acute myeloid leukemia.

Die Pharmazie - 1 Mar 2013

Chenjiao Yao, Zili Fan, Haibin Chen, Ying Liu, Sheng Xiao, Lihua Huang, Wei Du

Abstract excerpt

We investigated the possible association of Interleukin-10 (IL-10) single nucleotide polymorphisms (SNPs) and susceptibility to acute myeloid leukemia (AML) in 115 AML patients and 137 gender- and age-matched controls. Genetic analysis of IL-10 SNPs at -819 and -592 was carried out by polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP). Results revealed that the -819AA genotype...

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PMID: 23556339

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

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