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Article

Associations of IL-10 gene polymorphisms with acute myeloid leukemia in Hunan, China.

Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2013

Yao Chen-Jiao, Du Wei, Chen Hai-Bing, Xiao Sheng, Wang Cheng-Hong, Fan Zi-Li

Abstract excerpt

We investigated the possible association of interleukin-10 (IL-10) single nucleotide polymorphisms (SNPs) and susceptibility to acute myeloid leukemia (AML) in 115 patients and 137 healthy controls. Genetic analysis of IL-10 SNPs at -819 and -592 was carried out with the polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) approach. The IL-10 mRNA expression of AML patients and controls...

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Identifiers

PMID: 23725154
DOI: 10.7314/apjcp.2013.14.4.2439

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