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Article

Cell type of origin as well as genetic alterations contribute to breast cancer phenotypes.

Oncotarget - 20 Apr 2015

Bhagirath Divya, Zhao Xiangshan, West William W, Qiu Fang, Band Hamid, Band Vimla

Abstract excerpt

Breast cancer is classified into different subtypes that are associated with different patient survival outcomes, underscoring the importance of understanding the role of precursor cell and genetic alterations in determining tumor subtypes. In this study, we evaluated the oncogenic phenotype of two distinct mammary stem/progenitor cell types designated as K5+/K19- or K5+/K19+ upon introduction of identical...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 25940703
DOI: 10.18632/oncotarget.3379
PMCID: PMC4496199

Genes

EGFR

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