Article
Phenotypic and molecular characterization of the claudin-low intrinsic subtype of breast cancer.
Breast cancer research : BCR - 1 Jan 2010
Prat Aleix, Parker Joel S, Karginova Olga, Fan Cheng, Livasy Chad, Herschkowitz Jason I, He Xiaping, Perou Charles M
Abstract excerpt
INTRODUCTION: In breast cancer, gene expression analyses have defined five tumor subtypes (luminal A, luminal B, HER2-enriched, basal-like and claudin-low), each of which has unique biologic and prognostic features. Here, we comprehensively characterize the recently identified claudin-low tumor subtype. METHODS: The clinical, pathological and biological features of claudin-low tumors were compared to the other...
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