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Article

Gene dosage imbalances: action, reaction, and models.

Trends in biochemical sciences - 1 Jun 2015

Veitia Reiner A, Potier Marie Claude

Abstract excerpt

Single-gene deletions, duplications, and misregulation, as well as aneuploidy, can lead to stoichiometric imbalances within macromolecular complexes and cellular networks, causing their malfunction. Such alterations can be responsible for inherited or somatic genetic disorders including Mendelian...

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Identifiers

PMID: 25937627
DOI: 10.1016/j.tibs.2015.03.011

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25937627-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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