Article
The association between 38 previously reported polymorphisms and psoriasis in a Polish population: High predicative accuracy of a genetic risk score combining 16 loci.
PloS one - 1 Jan 2017
Kisiel Bartłomiej, Kisiel Katarzyna, Szymański Konrad, Mackiewicz Wojciech, Biało-Wójcicka Ewelina, Uczniak Sebastian, Fogtman Anna, Iwanicka-Nowicka Roksana, Koblowska Marta, Kossowska Helena, Placha Grzegorz, Sykulski Maciej, Bachta Artur, Tłustochowicz Witold, Płoski Rafał, Kaszuba Andrzej
Abstract excerpt
OBJECTIVES: To confirm the association of previously discovered psoriasis (Ps) risk loci with the disease in a Polish population and to create predictive models based on the combination of these single nucleotide polymorphisms (SNPs). MATERIAL AND METHODS: Thirty-eight SNPs were genotyped in 480 Ps patients and 490 controls. Alleles distributions were compared between patients and controls, as well as between...
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