Article
Breast cancer intra-tumor heterogeneity.
Breast cancer research : BCR - 20 May 2014
Martelotto Luciano G, Ng Charlotte K Y, Piscuoglio Salvatore, Weigelt Britta, Reis-Filho Jorge S
Abstract excerpt
In recent years it has become clear that cancer cells within a single tumor can display striking morphological, genetic and behavioral variability. Burgeoning genetic, epigenetic and phenomenological data support the existence of intra-tumor genetic heterogeneity in breast cancers; however, its basis is yet to be fully defined. Two of the most widely evoked concepts to explain the origin of heterogeneity within...
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