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Article

Intratumor heterogeneity: Nature and biological significance

1 Nov 2013

Abstract excerpt

Intratumor heterogeneity inherent in the majority of human cancers is a major obstacle for a highly efficient diagnosis and successful prognosis and treatment of these diseases. Being a result of clonal diversity within the same tumor, intratumor heterogeneity can be manifested in variability of genetic and epigenetic status, gene and protein expression, morphological structure, and other features of the tumor....

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Identifiers

PMID: 24460935
DOI: 10.1134/s0006297913110011

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