Article
Intratumor Heterogeneity in Breast Cancer.
Advances in experimental medicine and biology - 1 Jan 2016
Beca Francisco, Polyak Kornelia
Abstract excerpt
Intratumor heterogeneity is the main obstacle to effective cancer treatment and personalized medicine. Both genetic and epigenetic sources of intratumor heterogeneity are well recognized and several technologies have been developed for their characterization. With the technological advances in recent years, investigators are now elucidating intratumor heterogeneity at the single cell level and in situ. However,...
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