Article
The type 2 diabetes risk allele of TMEM154-rs6813195 associates with decreased beta cell function in a study of 6,486 Danes.
PloS one - 1 Jan 2015
Harder Marie Neergaard, Appel Emil Vincent Rosenbaum, Grarup Niels, Gjesing Anette Prior, Ahluwalia Tarunveer S, Jørgensen Torben, Christensen Cramer, Brandslund Ivan, Linneberg Allan, Sørensen Thorkild I A, Pedersen Oluf, Hansen Torben
Abstract excerpt
OBJECTIVES: A trans-ethnic meta-analysis of type 2 diabetes genome-wide association studies has identified seven novel susceptibility variants in or near TMEM154, SSR1/RREB1, FAF1, POU5F1/TCF19, LPP, ARL15 and ABCB9/MPHOSPH9. The aim of our study was to investigate associations between these novel risk variants and type 2 diabetes and pre-diabetic traits in a Danish population-based study with measurements of...
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