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Article

Novel meta-analysis-derived type 2 diabetes risk loci do not determine prediabetic phenotypes.

PloS one - 20 Aug 2008

Staiger Harald, Machicao Fausto, Kantartzis Konstantinos, Schäfer Silke A, Kirchhoff Kerstin, Guthoff Martina, Silbernagel Günther, Stefan Norbert, Fritsche Andreas, Häring Hans-Ulrich

Abstract excerpt

BACKGROUND: Genome-wide association (GWA) studies identified a series of novel type 2 diabetes risk loci. Most of them were subsequently demonstrated to affect insulin secretion of pancreatic beta-cells. Very recently, a meta-analysis of GWA data revealed nine additional risk loci with still undefined roles in the pathogenesis of type 2 diabetes. Using our thoroughly phenotyped cohort of subjects at an increased...

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Source

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Identifiers

PMID: 18714373
DOI: 10.1371/journal.pone.0003019
PMCID: PMC2500187

Genes

ADAMTS9
VEGFA
DCD
JAZF1
NOTCH2
TSPAN8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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