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Article

Tumor and Patient Characteristics of Individuals with Mismatch Repair Deficient Colorectal Cancer.

Digestion - 1 Jan 2015

Waldmann Elisabeth, Ferlitsch Monika, Binder Nicolas, Sellner Franz, Karner Josef, Heinisch Birgit, Klimpfinger Martin, Trauner Michael

Abstract excerpt

AIMS: To investigate tumor and patient characteristics of individuals with mismatch repair (MMR)-deficient colorectal carcinomas. METHODS: We immunhistochemically investigated tissue samples of 307 consecutive patients with colorectal cancer for defects in DNA MMR proteins (hMLH1, hMSH2, hMSH6, hPMS2) and those with mutations further for microsatellite instability (MSI) and BRAF V600E mutations. RESULTS: 32/308...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 25924923
DOI: 10.1159/000381284

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BRAF

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