Article
Telomerecat: A ploidy-agnostic method for estimating telomere length from whole genome sequencing data.
Scientific reports - 22 Jan 2018
Farmery James H R, Smith Mike L, Lynch Andy G
Abstract excerpt
Telomere length is a risk factor in disease and the dynamics of telomere length are crucial to our understanding of cell replication and vitality. The proliferation of whole genome sequencing represents an unprecedented opportunity to glean new insights into telomere biology on a previously unimaginable scale. To this end, a number of approaches for estimating telomere length from whole-genome sequencing data...
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