Effect of carboxylesterase 1 c.428G > A single nucleotide variation on the pharmacokinetics of quinapril and enalapril.

doi:10.1111/bcp.12667

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Article

Effect of carboxylesterase 1 c.428G > A single nucleotide variation on the pharmacokinetics of quinapril and enalapril.

British journal of clinical pharmacology - 1 Nov 2015

Tarkiainen E Katriina, Tornio Aleksi, Holmberg Mikko T, Launiainen Terhi, Neuvonen Pertti J, Backman Janne T, Niemi Mikko

Abstract excerpt

AIM: The aim of the present study was to investigate the effects of the carboxylesterase 1 (CES1) c.428G > A (p.G143E, rs71647871) single nucleotide variation (SNV) on the pharmacokinetics of quinapril and enalapril in a prospective genotype panel study in healthy volunteers. METHODS: In a fixed-...

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PMID: 25919042
DOI: 10.1111/bcp.12667
PMCID: PMC4631185

Genes

CES1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25919042-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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