Article
Survivin -31G/C promoter polymorphism and sporadic colorectal cancer.
International journal of colorectal disease - 1 Feb 2009
Gazouli Maria, Tzanakis Nikolaos, Rallis George, Theodoropoulos George, Papaconstantinou Ioannis, Kostakis Alkiviadis, Anagnou Nicholas P, Nikiteas Nikolaos
Abstract excerpt
INTRODUCTION: Survivin is an apoptotic inhibitor, plays an important role in cell cycle regulation, and may be involved in the development and progression of cancer. A common polymorphism at the survivin gene promoter (-31 G/C) has been shown to influence survivin expression and the risk for cancer. AIM: The aim of the present study was to investigate whether this polymorphism could be involved in the sporadic...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
