Article
The association between the survivin -31G/C promoter polymorphism and hepatocellular carcinoma risk in a Turkish population.
Cancer epidemiology - 1 Dec 2011
Bayram Süleyman, Akkız Hikmet, Bekar Aynur, Akgöllü Ersin
Abstract excerpt
BACKGROUND: Survivin, a member of the inhibitor of apoptosis protein family, functions as a key regulator of apoptosis and cell cycle regulation. A common single nucleotide polymorphism (-31G>C) at the survivin promoter has been extensively studied in various cancers and reported to influence survivin expression, but its association with hepatocellular carinoma (HCC) has yet to be investigated. The aim of the...
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