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Article

A Multivariate Computational Method to Analyze High-Content RNAi Screening Data.

Journal of biomolecular screening - 1 Sept 2015

Rameseder Jonathan, Krismer Konstantin, Dayma Yogesh, Ehrenberger Tobias, Hwang Mun Kyung, Airoldi Edoardo M, Floyd Scott R, Yaffe Michael B

Abstract excerpt

High-content screening (HCS) using RNA interference (RNAi) in combination with automated microscopy is a powerful investigative tool to explore complex biological processes. However, despite the plethora of data generated from these screens, little progress has been made in analyzing HC data using multivariate methods that exploit the full richness of multidimensional data. We developed a novel multivariate...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 25918037
DOI: 10.1177/1087057115583037
PMCID: PMC5377593

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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