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Article

A novel phenotypic dissimilarity method for image-based high-throughput screens.

BMC bioinformatics - 21 Nov 2013

Zhang Xian, Boutros Michael

Abstract excerpt

BACKGROUND: Discovering functional relationships of genes through cell-based phenotyping has become an important approach in functional genomics. High-throughput imaging offers the ability to quantitatively assess complex phenotypes after perturbation by RNA interference (RNAi). Such image-based high-throughput RNAi screening studies have facilitated the discovery of novel components of gene networks and their...

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Identifiers

PMID: 24256072
DOI: 10.1186/1471-2105-14-336
PMCID: PMC4225524

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