Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

SLCO1B1 genetic variants, long-term low-density lipoprotein cholesterol levels and clinical events in patients following cardiac catheterization.

Pharmacogenomics - 1 Jan 2015

Li Josephine H, Suchindran Sunil, Shah Svati H, Kraus William E, Ginsburg Geoffrey S, Voora Deepak

Abstract excerpt

AIM: SLCO1B1 variants are associated with intermediate outcomes that may increase risk of death/myocardial infarction (MI) in statin-treated patients. PATIENTS & METHODS: In high-risk Caucasians undergoing cardiac catheterization, we tested the association between rs4149056/625T>C and rs2306283/492A>G with low-density lipoprotein cholesterol (LDL-c) over 3 years (n = 1402) and death/MI over 6 years (n = 2994),...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cardiac Catheterization
Share to Cholesterol, LDL
Share to Hydroxymethylglutaryl-CoA Reductase Inhibitors
Share to Liver-Specific Organic Anion Transporter 1
Share to Myocardial Infarction
Share to Organic Anion Transporters
Share to Registries
Share to Survival Analysis

Source

Open in PubMed Open full text

Identifiers

PMID: 25916517
DOI: 10.2217/pgs.15.2
PMCID: PMC4719145

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

SLCO1B1 genetic variants, long-term low-density lipoprotein cholesterol levels and clinical events in patients following cardiac catheterization.PMID 25916517Read ↗

Possible gene-gender interaction between the SLCO1B1 polymorphism and statin treatment efficacy.Semantic proximity Read ↗

Associations between four polymorphisms of the SLCO1B1 and effectiveness of the statins: a meta-analysis.Semantic proximity Read ↗

Point-Counterpoint: SLCO1B1 Genotyping for Statins.Semantic proximity Read ↗

Meta-Analysis of the SLCO1B1 c.521T>C Variant Reveals Slight Influence on the Lipid-Lowering Efficacy of Statins.Semantic proximity Read ↗

The effects of a single nucleotide polymorphism in SLCO1B1 on the pharmacodynamics of pravastatin.Semantic proximity Read ↗

Pharmacogenetic interactions between ABCB1 and SLCO1B1 tagging SNPs and the effectiveness of statins in the prevention of myocardial infarction.Semantic proximity Read ↗

Statin treatment effectiveness and the SLCO1B1*5 reduced function genotype: Long-term outcomes in women and men.Semantic proximity Read ↗

Statin treatment effectiveness and the <i>SLCO1B1</i>*5 reduced function genotype: long-term outcomes in women and menSemantic proximity Read ↗

Genetic variation at the SLCO1B1 gene locus and low density lipoprotein cholesterol lowering response to pravastatin in the elderly.Semantic proximity Read ↗

Failure to replicate an association of SNPs in the oxidized LDL receptor gene (OLR1) with CAD.Semantic proximity Read ↗

The Effect of Genetic Polymorphisms in SLCO2B1 on the Lipid-Lowering Efficacy of Rosuvastatin in Healthy Adults with Elevated Low-Density Lipoprotein.Semantic proximity Read ↗

Lack of association between SLCO1B1 polymorphism and the lipid-lowering effects of atorvastatin and simvastatin in Chinese individuals.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.