Article
Pharmacogenetically relevant polymorphisms in Portugal.
Pharmacogenomics - 1 Jul 2007
Oliveira E, Marsh S, van Booven D J, Amorim A, Prata M J, McLeod H L
Abstract excerpt
OBJECTIVE: Most drugs are developed based on data from European-derived 'reference' populations; however, clinically relevant DNA polymorphisms often demonstrate population-specific patterns of allele frequencies. Given that the knowledge of the frequency distribution of functional polymorphisms in a population may guide national planning for selection of therapeutic options, in the present study we examined the...
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