Article
Immunohistochemical expression of stem cell markers in pheochromocytomas/paragangliomas is associated with SDHx mutations.
European journal of endocrinology - 1 Jul 2015
Oudijk L, Neuhofer C M, Lichtenauer U D, Papathomas T G, Korpershoek E, Stoop H, Oosterhuis J W, Smid M, Restuccia D F, Robledo M, de Cubas A A, Mannelli M, Gimenez-Roqueplo A P, Dinjens W N M, Beuschlein F, de Krijger R R
Abstract excerpt
OBJECTIVE: Pheochromocytomas (PCCs) are neuroendocrine tumors that occur in the adrenal medulla, whereas paragangliomas (PGLs) arise from paraganglia in the head, neck, thorax, or abdomen. In a variety of tumors, cancer cells with stem cell-like properties seem to form the basis of tumor initiati...
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