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Article

SOX2+ sustentacular cells are stem cells of the postnatal adrenal medulla

2 Jan 2025

Abstract excerpt

Abstract Renewal of the catecholamine-secreting chromaffin cell population of the adrenal medulla is necessary for physiological homeostasis throughout life. Definitive evidence for the presence or absence of an adrenomedullary stem cell has been enigmatic. In this work, we demonstrate that a subset of sustentacular cells endowed with a support role, are in fact adrenomedullary stem cells. Through genetic tracing...

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PMID: 39747853
DOI: 10.1038/s41467-024-55289-5

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