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Cancer Stem Cells in Pheochromocytoma and Paraganglioma

25 Feb 2020

Abstract excerpt

Pheochromocytoma (PCC) and paraganglioma (PGL) are rare neuroendocrine tumors associated with high cardiovascular morbidity and variable risk of malignancy. The current therapy of choice is surgical resection. Nevertheless, PCCs/PGLs are associated with a lifelong risk of tumor persistence or recurrence. A high rate of germline or somatic mutations in numerous genes has been found in these tumors. For some, the...

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PMID: 32158431
DOI: 10.3389/fendo.2020.00079

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