Article
Targeted sequencing with enrichment PCR: a novel diagnostic method for the detection of EGFR mutations.
Oncotarget - 30 May 2015
Kang Suki, Kim Baek Gil, Han Hyun Ho, Lee Joo Hyun, Kim Ji Eun, Shim Hyo Sup, Cho Nam Hoon
Abstract excerpt
Epidermal growth factor receptor (EGFR) is an important mediator of tumor cell survival and proliferation. The detection of EGFR mutations can predict prognoses and indicate when treatment with EGFR tyrosine kinase inhibitors should be used. As such, the development of highly sensitive methods fo...
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