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Article

Detection and characterization of classical and "uncommon" exon 19 Epidermal Growth Factor Receptor mutations in lung cancer by pyrosequencing.

BMC cancer - 13 Mar 2013

Righi Luisella, Cuccurullo Alessandra, Vatrano Simona, Cappia Susanna, Giachino Daniela, De Giuli Paolo, Ardine Mara, Novello Silvia, Volante Marco, Scagliotti Giorgio V, Papotti Mauro

Abstract excerpt

BACKGROUND: The management of advanced stage non-small cell lung cancer is increasingly based on diagnostic and predictive analyses performed mostly on limited amounts of tumor tissue. The evaluation of Epidermal Growth Factor Receptor (EGFR) mutations have emerged as the strongest predictor of response to EGFR-tyrosine kinase inhibitors mainly in patients with adenocarcinoma. Several EGFR mutation detection...

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Identifiers

PMID: 23497146
DOI: 10.1186/1471-2407-13-114
PMCID: PMC3608975

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EGFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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