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Article

Substrate recognition and modification by the nosiheptide resistance methyltransferase.

PloS one - 1 Jan 2015

Yin Sitao, Jiang Hengyi, Chen Dongrong, Murchie Alastair I H

Abstract excerpt

BACKGROUND: The proliferation of antibiotic resistant pathogens is an increasing threat to the general public. Resistance may be conferred by a number of mechanisms including covalent or mutational modification of the antibiotic binding site, covalent modification of the drug, or the over-expression of efflux pumps. The nosiheptide resistance methyltransferase (NHR) confers resistance to the thiazole antibiotic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 25910005
DOI: 10.1371/journal.pone.0122972
PMCID: PMC4409310

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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