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Expression and promoter methylation status of <i>hMLH1</i> , <i>MGMT</i> , <i>APC,</i> and <i>CDH1</i> genes in patients with colon adenocarcinoma

23 Apr 2015

Abstract excerpt

Colorectal cancer (CRC) is the third most common cancer in men and the second in women worldwide. CRC development is the result of genetic and epigenetic alterations accumulation in the epithelial cells of colon mucosa. In the present study, DNA methylation, an epigenetic event, was evaluated in tumoral and matching normal epithelium in a cohort of 61 CRC patients. The results confirmed and expanded knowledge for...

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Share to Colorectal Cancer Screening and Detection
Share to Epigenetics and DNA Methylation
Share to Genetic factors in colorectal cancer

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PMID: 25908636
DOI: 10.1177/1535370215583800

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