Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Aberrant Methylation of<i>APC, MGMT, RASSF2A</i>, and<i>Wif-1</i>Genes in Plasma as a Biomarker for Early Detection of Colorectal Cancer

23 Sept 2009

Abstract excerpt

PURPOSE: To identify epigenetic molecular makers in plasma for the early detection of colorectal cancer. EXPERIMENTAL DESIGN: We retrospectively analyzed the methylation status of 10 genes in fresh-frozen tissues and corresponding plasma samples from 243 patients with stage I and II sporadic colorectal cancer, 276 healthy individuals, and plasma from 64 colorectal adenoma patients using methylation-specific PCR....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Cells and Metastasis
Share to Cancer Genomics and Diagnostics
Share to Epigenetics and DNA Methylation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 19773381
DOI: 10.1158/1078-0432.ccr-09-0111

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Aberrant Methylation of<i>APC, MGMT, RASSF2A</i>, and<i>Wif-1</i>Genes in Plasma as a Biomarker for Early Detection of Colorectal CancerPMID 19773381Read ↗

The methylation of <i>SDC2</i> and <i>TFPI2</i> defined three methylator phenotypes of colorectal cancerSemantic proximity Read ↗

DNA methylation patterns in blood of patients with colorectal cancer and adenomatous colorectal polypsSemantic proximity Read ↗

Blood-based DNA Methylation Biomarkers for Early Detection of Colorectal CancerSemantic proximity Read ↗

Colorectal adenoma and cancer detection based on altered methylation pattern of SFRP1, SFRP2, SDC2 , and PRIMA1 in plasma samplesSemantic proximity Read ↗

Analysis of DNA Methylation in Bowel Lavage Fluid for Detection of Colorectal CancerSemantic proximity Read ↗

Methylation status of the APC and RASSF1A promoter in cell-free circulating DNA and its prognostic role in patients with colorectal cancerSemantic proximity Read ↗

A panel of DNA methylation signature from peripheral blood may predict colorectal cancer susceptibilitySemantic proximity Read ↗

Methylation of the Polycomb Group Target Genes Is a Possible Biomarker for Favorable Prognosis in Colorectal CancerSemantic proximity Read ↗

Enhanced Diagnostic Efficiency of a Novel Fecal Methylated Gene Model for Early Colorectal Cancer DetectionSemantic proximity Read ↗

Quantitative Detection of Promoter Hypermethylation in Multiple Genes in the Serum of Patients with Colorectal CancerSemantic proximity Read ↗

Progressive alteration of DNA methylation of Alu, MGMT, MINT2, and TFPI2 genes in colonic mucosa during colorectal cancer developmentSemantic proximity Read ↗

Clinical Applications of DNA Methylation Biomarkers in Colorectal CancerSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.